EpiDiP/NanoDiP: a versatile unsupervised machine learning edge computing platform for epigenomic tumour diagnostics

Abstract DNA methylation analysis based on supervised machine learning algorithms with static reference data, allowing diagnostic tumour typing with unprecedented precision, has quickly become a new standard of care.Whereas genome-wide diagnostic methylation profiling is mostly performed on microarrays, an increasing number of institutions addition

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Estimation of Physical Activity Levels Using Cell Phone Questionnaires: A Comparison With Accelerometry for Evaluation of Between-Subject and Within-Subject Variations

BackgroundPhysical activity promotes health and longevity.Further elaboration of the role of physical activity for human health in epidemiological studies on large samples requires accurate methods that are easy to use, cheap, and possible to repeat.The use of telecommunication technologies such as cell phones is highly interesting in this respect.

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An Improved Algorithm for the Retrieval of the Antarctic Sea Ice Freeboard and Thickness from ICESat-2 Altimeter Data

ICESat-2 altimeter data could be used to estimate sea ice freeboard and thickness values with a higher measuring accuracy than that achievable with data provided by previous altimeter satellites.This study developed an improved algorithm considering variable lead proportions based on the lowest point method to derive the sea surface height for the

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